Hiprex (Methenamine Hippurate)

Methenamine (meth en' a meen) Hiprex® Urex® Mandelamine

Methenamine, an antibiotic, eliminates bacteria that cause urinary tract infections. It usually is used on a long-term basis to treat chronic infections and to prevent recurrence of infections. Antibiotics will not work for colds, flu, or other viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Methenamine comes as a tablet and a liquid to take by mouth. It usually is taken either two times a day (every 12 hours) or four times a day (after meals and at bedtime). Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take methenamine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the coated tablets whole. Do not crush or break them. Take the tablets with a full glass of water or with food. Shake the liquid well before each use to mix the drug evenly.

Before taking methenamine, tell your doctor and pharmacist if you are allergic to methenamine, aspirin, tartrazine (a yellow dye in some processed foods and drugs), or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antacids, sulfamethizole, diuretics ('water pills'), and vitamins. tell your doctor if you have or have ever had kidney or liver disease. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking methenamine, call your doctor.

Methenamine may cause an upset stomach. Take methenamine with food or milk.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Methenamine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: upset stomach vomiting diarrhea stomach cramps loss of appetite If you experience any of the following symptoms, call your doctor immediately: skin rash hives itching (allergic reaction) If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to methenamine. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.